Dr. Hongbin Cheng
functional neurosurgery
Specialist in:
Stem cell research and treatment
Department:
Functional Neurosurgery
Specialized in treating Diseases:
Cerebral Palsy, Traumatic Brain Injury, Spinal Cord Injuries,Sequelae of Cerebral Hemorrhage and Cerebral Thrombosis, Diabetes, Liver Cirrhosis, Premature Ovarian Failure, Male Sexual Dysfunction, chronic knee osteoarthritis etc.
Social Appointments:

- Part-time Professor at Heilongjiang University of Traditional Chinese Medicine and Xinxiang Medical University  
- Member of the Laser Medicine Group, Chinese Medical Association  
- Youth Committee Member of the Chinese Anti-Cancer Association  
- Standing Committee Member of the Minimally Invasive Alliance's Critical Care Committee

Dr. Cheng is a renowned stem cell expert with a long - standing reputation in the field. Holding a PhD from Harbin Medical University, he has published numerous high - impact research papers, significantly advancing our understanding of stem cell applications in regenerative medicine. Dr. Cheng has vast experience in both basic stem cell research for more than 20 years and clinical treatment for more than 15 years. He is one of the pioneer Chinese expert to take outbound stem cell treatment for foreign patients. His medical team has participated in over thirty thousands stem cell transplantation cases for Chinese and foreign patients.

Dr. Cheng is good at the diagnosis, treatment and post-treatment rehabilitation technology of cerebral palsy, brain injury, spinal cord injury, cerebral hemorrhage, cerebral thrombosis sequelae. He participated in the first CT guided stereotactic brain stem cell transplantation, interventional treatment of spinal cord injury, diabetes, cirrhosis of the liver. At present, he is mainly responsible for stem cell transplantation related work, including surgical plan, the specific operation and new transplantation methods development.


Research programs

1.Development of stem cell technology and products for treating Cerebrovascular Disease Sequelae. National 863 Stem Cell and Tissue Engineering project (2006AA02A115).

2.Experimental research on neural stem cell transplantation to treat Temporal Lobe Epilepsy. Nature Science Foundation of China (30240052).

3.Experimentation and clinical research on traumatic brain injury and treatment with mild hypothermia. The 9th, Five-Year Key Project of Heilongjiang Province(G98L19-13).

Research Papers of Our Experts – SCI (Science Citation Indexsci) Included

1.Treatment of one case of cerebral palsy combined with posterior visual pathway injury using autologous bone marrow mesenchymal stem cells

https://pubmed.ncbi.nlm.nih.gov/22607263/

2.Umbilical cord mesenchymal stem cell transplantation significantly improves neurological function in patients with sequelae of traumatic brain injury

http://www.ncbi.nlm.nih.gov/pubmed/23942181

3.Comparative analysis of curative effect of CT-guided stem cell transplantation and open surgical transplantation for sequelae of spinal cord injury

https://pubmed.ncbi.nlm.nih.gov/24355001/

4.Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke

http://www.ncbi.nlm.nih.gov/pubmed/20727165

5.Effects of bone marrow mesenchymal stromal cells on gross motor function measure scores of children with cerebral palsy: a preliminary clinical study

http://www.ncbi.nlm.nih.gov/pubmed/24100132

6.Analysis of the causes and types of traumatic spinal cord injury based on 561 cases in China from 2001 to 2010

http://www.ncbi.nlm.nih.gov/pubmed/23184031

7.Human mesenchymal stem cell transplantation protects against cerebral ischemic injury and upregulates interleukin-10 expression in Macacafascicularis

http://www.ncbi.nlm.nih.gov/pubmed/20353760

8.Serial 18F-FDG PET demonstrates benefit of human mesenchymal stem cells in treatment of intracerebral hematoma: a translational study in a primate model

http://www.ncbi.nlm.nih.gov/pubmed/21149480

9.Transplantation of human bone marrow-derived mesenchymal stem cells promotes behavioral recovery and endogenous neurogenesis after cerebral ischemia in rats

http://www.ncbi.nlm.nih.gov/pubmed/20977892

10.Transplantation of Flk-1+ human bone marrow-derived mesenchymal stem cells promotes angiogenesis and neurogenesis after cerebral ischemia in rats

http://www.ncbi.nlm.nih.gov/pubmed/21692879

11.In vitro behavior of neural stem cells in response to different chemical functional groups

http://www.ncbi.nlm.nih.gov/pubmed/19026444

12.Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614414/

13.Induction of functional recovery by co-transplantation of neural stem cells and Schwann cells in a rat spinal cord contusion injury model

http://www.ncbi.nlm.nih.gov/pubmed/17672216

14.Modulation and impact of class I major histocompatibility complex by neural stem cell-derived neurotrophins on neuroregeneration

http://www.ncbi.nlm.nih.gov/pubmed/16949763

15.Potential of stem cell based therapy and tissue engineering in the regeneration of the central nervous system

http://www.ncbi.nlm.nih.gov/pubmed/18460755

16.Differentiation of rat neural stem cells and its relationship with environment

http://www.ncbi.nlm.nih.gov/pubmed/15202858

17.Effect of rat Schwann cell secretion on proliferation and differentiation of human neural stem cells

http://www.ncbi.nlm.nih.gov/pubmed/12747012

18.Schwann cells transplantation promoted and the repair of brain stem injury in rats

http://www.ncbi.nlm.nih.gov/pubmed/14631826

19.Differentiation of rat embryonic neural stem cells promoted by co-cultured Schwann cell

http://www.ncbi.nlm.nih.gov/pubmed/12781052

20.Protective effect of melatonin on neural cells against the cytotoxicity of oxyradicals

http://www.ncbi.nlm.nih.gov/pubmed/12899398

21.BMP4 is insufficient to differentiate umbilical cord mesenchymal stem cells into germ cell-like cells in vitro

https://pubmed.ncbi.nlm.nih.gov/35072224/

22.Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes

https://pubmed.ncbi.nlm.nih.gov/35126831/

23.Sustainable Production and Activity Determination of Serum‑Free Conditioned Medium from Menstrual Blood‑Derived Endometrial Stem Cells

https://pubmed.ncbi.nlm.nih.gov/36327033/

24.Menstrual Blood–Derived Endometrial Stem Cell Transplantation Improves Male Reproductive Dysfunction in T1D Mice by Enhancing Antioxidative Capacity

https://pubmed.ncbi.nlm.nih.gov/38396297/

Funded Research Projects

1.Neural stem cell transplantation to repair dysfunction after Cerebral Infarction in monkeys. The 10th Huo Yingdong Education Foundation Fellowship for Young Teachers of Higher Education (101043)

2.Research on the underlying mechanism of neural stem cell transplantation to treat Motor Neuron Disease. The New-Century Notable Talent Culture Plan of the Chinese Ministry of Education.

3.Combination of neural stem cells and tissue engineering to treat post Cerebral Haemorrhage neurological dysfunction in monkeys. Nature Science Foundation of China (30371452)

4. Combination of neural stem cells and tissue engineering to treat post Cerebral Haemorrhage Neurological Dysfunction. Beijing New Star of Science and Technology Culture Plan (H020821360130)

5. Combination of neural stem cells and tissue engineering to treat post Cerebral Haemorrhage Neurological Dysfunction in monkeys. International science and technology cooperation project of Beijing in 2003(2003012)

6. Neural stem cell transplantation to repair post Cerebral Haemorrhage dysfunction in rats. Beijing Notable Talent Culture Project. 

7. Preclinical research on neural stem cell transplantation to treat Stroke Sequelae. China Postdoctoral Foundation Culture and transplantation of human multipotent neural stem cells: a pilot study. Beijing Young Research Culture Foundation

8. Preclinical and clinical study on the relationship between free radicals and delayed secondary brain injury after hypothermia protection. Research Foundation for Young Scientists (Heilongjiang Province) (Q99-19)

CCTV Special Media Reports

Memo: CCTV—China Central Television (the largest national television of China)

The Hemisphere Miracle: A Traumatic Brain Injury Case   

https://tv.cctv.com/2010/04/30/VIDE1355515562580202.shtml 

From Broken Neck to Recovery: A Spinal Cord Injury Breakthrough

https://tv.cctv.cn/2011/01/12/VIDEcEpJtSO2PNHsDTKk4Kp3110112.shtml

Twins Overcoming Cerebral Palsy

https://tv.cctv.com/2010/01/30/VIDE1355513142535320.shtml

Where a Mother’s Love Holds Up the Sky: Twin Sisters with Cerebral Palsy

https://tv.cctv.com/2010/01/28/VIDE1407404542636165.shtml

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