Traumatic-Brain-Injury-Case-William

Case：William from Ireland

Nationality：

Ireland

Age：

22 years old

Diagnosis：

Traumatic Brain Injury

Admission Date：

Dec. 2015

Background

William, a 22 - year - old man hailing from Ireland, unfortunately sustained a traumatic brain injury following a car accident in 2011. On January 12, 2015, he underwent the first round of stem cell transplantation treatment, marking a significant step in his journey towards potential recovery.

Pre-Treatment Condition（Before Stem Cell Treatment）

1. Aggressive behavior (e.g., assaulting caregivers);
2. Upper limbs: High muscle tone with paradoxical weakness; unable to extend left hand voluntarily;
3. Lower limbs: Low muscle strength with elevated tone; non-ambulatory (unable to stand/walk);
4. Loss of bladder/bowel control, severely impacting daily care.

Treatment Plan

One course of stem cell therapy
Surgical method: Lumbar puncture+Stereotactic brain surgery
Efficacy monitoring plan over 6 to 12 months post-treatment

After the First Course ofTreatment(6Months)【Start数字编号】

Behavioral & Motor Function: Mood stabilization (no aggression reported);

Upper limbs: Reduced spasticity, improved strength; regained voluntary movement (independent left-hand extension);

3. Lower Limb Mobility: Achieved 2-minute independent standing and 1-minute unsupported walking (functional mobility recovery);

4. Sensory & Self-Awareness: Restored bladder awareness (verbally requests diaper changes), first observed in 3 years;

5. Daily Activity Reintegration: Engaged in leisure activities (e.g., TV watching), marking partial return to pre-illness routines.

【End数字编号】

Symptom	Improvement
Behavioral Issues	Mood stabilization (no aggression reported);\| high upper-limb spasticity with paradoxical weakness; unable to extend left hand; reduced spasticity; improved strength; voluntary left-hand extension.
Lower Limb Dysfunction	Achieves 2-minute independent standing and 1-minute unsupported walking; elevated lower-limb tone with low strength; improved leg extension and functional mobility.
Sensory/Bladder Impairment	Restored bladder awareness (requests diaper changes).
Restricted Daily Activities	Engages in leisure activities (e.g., TV watching), partial return to normal routines.

Progress Summary & Future Outlook

The patient's recent progress is highly encouraging, foreshadowing a promising future. As time goes on, with consistent rehabilitation, the muscle strength in his upper and lower limbs will likely keep growing. He may soon be able to walk longer distances and perform more complex physical tasks independently. The regained ability to sense urination could be a starting point for full bladder and bowel control restoration. His new-found interest in watching TV also implies better cognitive engagement. Overall, he is on a positive trajectory towards a more normal and fulfilling life.