Cerebral-Palsy-Case-Sofiia

Case: Sofiia from Kyrgyzstan

Nationality：

Kyrgyzstan

Age：

4 years old

Diagnosis：

Cerebral Palsy

First Admission Date：

May 2017

Background

Sofiia, a 4 -year-7 -month-old girl from Kyrgyzstan, was born healthy with an Apgar score of 7 - 8 and normal physiological indicators.

At 2 months old, after vaccination, she had partial hand attacks and weight loss. On September 1, 2009, she suddenly fell ill, was hospitalized due to coma and spent a week in the resuscitation unit. After waking up, she lost skills like swallowing, sucking, and responsiveness. Diagnosed with cerebral palsy and epilepsy at 4 months, she took antiepileptic drugs (Keppra, Depakine, Potassium Bromide) and underwent rehabilitation. EEG showed no epilepsy in 2015, so she stopped the drugs. In 2016, nutritious supplements helped her gain weight, boost immunity, and improve appetite.

From September 2016, she received rehabilitation at Guangdong 999 Brain Hospital. With limited progress, she was admitted to the stem cells department in Beijing on May 18, 2017. During four treatments, she had 7 physical training and massage sessions.

Pre-Treatment Condition (Before the First Course of Treatment)

1. Severe Motor Delay:
- GMFCS Level V (no sitting/standing/head control);
- Hypotonia → Chaotic lower limb movements;
2. Global Developmental Delay:
- Cognitive/adaptive skills below age norms;
3. Communication Deficit:
- Intact hearing; absent expressive/receptive language;
4. Fine Motor Impairment:
- Crude grasping only; poor hand-eye coordination.

Treatment Plan

Two weeks of stem cell therapy
Surgical method: Lumbar puncture
Efficacy monitoring plan over 6 to 12 months post-treatment

After the First Course of Treatment ( 6 months)

1. General well-being improved(mood, appetite, sleep);
2. Cognitive gains: ↑ comprehension of conversations; faster responsiveness;
3. Expressive communication: ↑ facial expressions; social smiling;
4. Fine Motor Skills:
- ↑ Grip strength (firm object holding);
- ↑ Hand-eye coordination (accurate object placement post-PT);
Mobility: Assisted walking endurance ↑ (improved lower limb strength).

After the Second Course of Treatment ( 12 months)

1. ↑ General well-being(mood/appetite/sleep);
2. ↑ Comprehension(processes complex instructions);
3. ↑ Fine motor precision (accurate utensil use);
4. ↑ Social comfort (engages strangers easily);
5. Ongoing focus: Neck/waist strengthening exercises.

Symptom	Improvement
Low mood; poor appetite/sleep	↑ Mood/appetite; ↑ sleep quality
Global developmental delay (delayed comprehension)	Processes complex instructions; ↑ reaction speed
Crude grasping; poor hand-eye coordination	Precise grasping (utensil use); ↑ hand accuracy
Social withdrawal (anxiety/limited expressions)	Active social smiling; ↑ comfort with strangers
GMFCS Level V (no sitting/standing/head control)	↑ Assisted walking endurance (needs core training)
Lower limb strength - Absent neck/waist control	↑ Lower limb strength - Ongoing core strengthening

Progress Summary & Future Outlook

The patient's current positive progress bodes well for the future. With a better state of spirit, appetite, and sleep, their overall physical and mental health will continue to strengthen. As the comprehension ability further develops, they'll be able to engage more deeply in learning and social communication.

In the long run, with unremitting efforts, the patient is likely to achieve a higher level of self- reliance and an improved quality of life.