Cerebral palsy case

Case: Lulu from China

Nationality：

China

Age：

7 years old

Diagnosis：

Cerebral palsy

First Admission Date：

Dec 2010

Second Admission Date：

Mar 2012

Background

Lulu (preterm, 1.5kg BW) developed postnatal hypoxia-induced spastic CP. 2010 MRI at Inner Mongolia Medical University Hospital showed:

1. Bilateral periventricular leukomalacia

2. Corpus callosum hypoplasia

Underwent two stem cell therapies (2010, 2012) with progressive functional gains. Featured on CCTV’s "Approaching Science" global broadcast, demonstrating neuroregenerative potential in CP management.

Pre-Treatment Condition (Before the First Course of Treatment)

Independent standing (~10 mins) with weak waist muscles, requiring hip elevation;
Unsteady independent walking (~10 steps);
Unable to squat and stand unaided;
Failed self-initiated standing from seated position;
Bilateral clumsy hand rotation movements;
Left hand rigidity (particularly during extension and two-finger pointing).

Treatment Plan

Two courses of stem cell therapy
Surgical method: Lumbar puncture and Stereotactic brain surgery
Efficacy monitoring plan over 12 to 18 months post-treatment

After the First Course of Treatment (15 months)

Marked truncal muscle improvement: independent standing without hip elevation;
Stable independent ambulation (200m+);
Achieves independent squat-stand transition;
Effortless sit-to-stand from seated positions;
Bilateral coordinated hand rotation;
Left hand fine motor precision (finger extension & two-finger pointing).

Symptom	Improvement
Weak truncal muscles requiring hip elevation	Independent standing with proper posture
Unsteady gait (10 steps)	Stable ambulation (200m+)
Failed squat-stand transition	Achieves dynamic posture transfer
Impaired sit-to-stand ability	Normalized transitional movement
Bilateral hand rotation discoordination	Improved bimanual coordination
Left hand rigidity (finger tasks)	Enhanced digital dexterity (precision grip)

Progress Summary & Future Outlook

Lulu's significant progress predicts continued functional gains. With targeted rehabilitation, expect enhanced:

• Muscle strength (GMFCS Level improvement potential)
• Dynamic balance (Berg Balance Scale ≥45)
• Bimanual coordination (AHA Score increase ≥20%)

Scheduled biannual assessments (GMFM-66/WeeFIM) will sustain and enhance outcomes. This neurorehabilitation synergy may enable advanced ADL independence and recreational mobility within 2 years.