Age：12 Years old

Nationality：China

Diagnosis：Autism

Admission Date：Jan 2014

Patient was born in full-term caesarean section, cried right after birth, no cyanosis. Normal motor development. Patient could speak single sound “mama” when he was 2 years old, and because of speech and mental development delay, he was diagnosed with autism in local hospital when turned 3, then had 1 month of rehabilitation training in a hospital in Guangxi province. With no obvious development, his mother took him home training by herself. He could speak simple words when turned 4 years old, and was diagnosed as “high functional autism” in Nanjing Brain Hospital when he was 5. He continuously accepted rehabilitation training, but the effect wasn’t well. he was admitted to our department in Jan 2nd, 2014.

• A bit less intelligent than his peers, fast and blurred speaking, can accomplish several instructions, has fine memory, comprehension and orientation.
• He does not cooperate the physical examination, pupils of both sides have equal size and shape, 3mm diameter, no sense of light in the left eye, both eyeballs have difficulty to move freely towards all directions and do not have strabismus, nystagmus nor diplopia.
• All limbs are flexible, grade 5 muscle strength and 0 muscle tension in both upper limbs, no tendon reflex, Hoffmann's sign (-), grade 5 muscle strength and 0 muscle tension in both lower limbs, tendon hyperreflexia, Babinski sign (-), ankle clonus (-). Soft neck, Kernig’ (-),
• Uncooperative in full body superficial sensation and bathyesthesia examination.

• One course of stem cell therapy
• Surgical method: Lumbar puncture
• Efficacy monitoring plan over 6 to 12 months post-treatment