Autism-Case-Wang-Xinyu

Wang Xinyu from China

Age：7 Years old

Nationality：China

Diagnosis：Autism

Admission Date：Jan 2013

Background

Patient was born asphyxia after birth and was diagnosed with autistic tendency when she turned 3 years old. Before admitting to our department, patient continuously accepted treatment in many professional medical institutions in Beijing and Shanghai with rehabilitation training, psychological counseling and drug therapy. Resulting in limited improvement with poor performance. The patient was admitted to our department on June 4th, 2013. After checking brain MRI and EEG, we found patient’s white matter development is abnormal and EEG is also abnormal.

Pre-Treatment Condition（Before Stem Cell Treatment）

Poor communication with people, unwilling to express her wishes；
2. Could say fewer words, only can make voice like "hey, oh, gee." Facial expression also is indifference；
3. Needs to remind to relieve the bowels, cannot take care of herself；
4. When goes out, the patient must be with adults following. If not, easy to get lost；
5. Although taking antiepileptic drugs, spasm happens occasionally；
6. Has self-destructive tendencies, also with mild attack tendency to people.

Treatment Plan

One course of stem cell therapy
Surgical method: Lumbar puncture
Efficacy monitoring plan over 6 to 12 months post-treatment

After the First Course ofTreatment (6 months)

The patient is willing to communicate with people, willing to laugh and express her wishes；
An increase in words and facial incontinence disappear；
The patient takes the initiative to hold the adult skirt when goes out；
Epilepsy is better controlled；
The patient is willing to play games with other children. Grumpy and self-destructive tendency ease and attack tendency disappear.

Category	Symptom	Improvement
Communication	Poor communication; reluctance to express wishes.	Willing to communicate, express needs, and smile.
Verbal Ability	Limited to sounds ("hey," "oh"); flat facial expressions.	Increased vocabulary; improved emotional expression.
Self-Care	Required reminders for toileting; dependent care.	Improved initiative (e.g., holding adult’s skirt for guidance).
Outdoor Safety	High risk of getting lost without adult supervision.	Actively seeks adult support when outdoors.
Seizure Control	Occasional spasms despite medication.	Better-controlled epilepsy.
Behavioral Tendencies	Self-harm and mild aggression toward others.	Reduced irritability; no self-harm/aggression.

Progress Summary & Future Outlook

With the remarkable progress from the first stem cell treatment, the future looks full of hope. As time goes on, continued treatment or further medical advancements might lead to even greater improvements.